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| 最近の主な論文・日本語総説 |
2011/8/14 更新 |
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Wang L, Nomura M, Goto Y, Tanaka K, Sakamoto R, Abe I, Sakamoto S, Shibata A, Enciso PL, Adachi M, Ohnaka K, Kawate H, Takayanagi R:
Smad2 disruption in the central nervous system leads to aberrant cerebellar development and early postnatal ataxia in mice.
J Biol Chem 286: 18766-18774, 2011
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Kawate H, Taketomi A, Watanabe T, Nomura M, Kato M, Sakamoto R, Ikegami T, Soejima Y, Maehara Y, Takayanagi R:
Hypophosphatemic osteomalacia as a long-term complication after liver transplantation.
Transplantation 91: e6-8, 2011
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Chen GC, Goto Y, Sakamoto R, Tanaka K, Matsubara E, Nakamura M, Zheng H, Lu J, Takayanagi R, Nomura M:
GLI1, a crucial mediator of sonic hedgehog signaling in prostate cancer, functions as a negative modulator for androgen receptor.
Biochem Biophys Res Commun 404: 809-815, 2011
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Iwatsuki K, Nomura M, Shibata A, Ichikawa R, Enciso L.M.P, Wang L, Takayanagi R. Torii K, Uneyama H:
Generation and characterization of T1R2-LacZ knock-in mouse.
Biochem Biophys Res Commun 402: 495-499, 2010
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Takimoto T, Wakabayashi Y, Sekiya T, Inoue N, Morita R, Ichiyama K, Takahashi R, Asakawa M, Muto G, Mori T, Hasegawa E, Shizuya S, Hara T, Nomura M, Yoshimura A:
Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.
J Immunol 185: 842-55, 2010
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Gushima M, Kawate H, Ohnaka K, Nomura M, Takayanagi R:
Raloxifene induces nuclear translocation of the estrogen receptor.
Mol Cell Endocrinol 319: 14-22, 2010
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Min L, Yanase T, Tanaka T, Fan W, Nomura M, Kawate H, Okabe T, Takayanagi R, Nawata H:
A novel synthetic androgen receptor ligand, S42, works as a selective androgen receptor modulator and possesses metabolic effects with little impact on the prostate.
Endocrinology 150: 5606-5616, 2009
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Ishihara N, Nomura M, Jofuku A et al.:
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Nat Cell Biol 11: 958-966, 2009
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Gondo S, Okabe T, Tanaka T, Morinaga H, Nomura M, Takayanagi R, Nawata H, Yanase T:
Adipose tissue-derived and bone marrow derived mesenchymal cells develop into different lineage of steroidogenic cells by forced expression of SF-1.
Endocrinology 149: 4717-4725, 2008
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Fan W, Yanase T, Nishi Y, Chiba S, Okabe T, Nomura M, Yoshimatsu H, Kato S, Takayanagi R, Nawata H:
Functional potentiation of leptin-stat3 signaling by the androgen receptor.
Endocrinology 149: 6028-6036, 2008
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Goto Y, Nomura M, Tanaka K, Kondo A, Morinaga H, Okabe T, Yanase T, Nawata H, Takayanagi R, Li E:
Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets.
Dev Dyn 236: 2865-2874, 2007
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Kawate H, Wu Y, Ohnaka K, Takayanagi R:
Mutual transactivational repression of Runx2 and the androgen receptor by an impairment of their normal compartmentalization.
J Steroid Biochem Mol Biol 105: 46-56, 2007
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Hollingshead HE, Morimura K, Adachi M, Kennett MJ, Billin AN, Willson TM, Gonzalez FJ,Peters JM:
PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.
Dig Dis Sci 52: 2912-2919, 2007
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Fan W, Yanase T, Morinaga H, Okabe T, Nomura M, Daitoku H, Fukamizu A, Kato S, Takayanagi R, Nawata H:
Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor.
J Biol Chem 282: 7329-7338, 2007
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Wu Y, Kawate H, Ohnaka K, Nawata H, Takayanagi R:
Nuclear compartmentalization of N-CoR and its interactions with steroid receptors.
Mol Cell Biol 26: 6633-6655, 2006
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Adachi M, Kurotani R, Morimura K, Shah Y, Sanford M, Madison BB, Gumucio DL, Marin HE, Peters JM, Young HA, Gonzalez FJ:
Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease.
Gut 55: 1104-13, 2006
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Tao R-H, Kawate H, Wu Y, Ohnaka K, Ishizuka M, Inoue A, Hagiwara H, Takayanagi R:
Testicular zinc finger protein recruits histone deacetylase 2 and suppresses the transactivation function and intranuclear foci formation of agonist-bound androgen receptor competitively with TIF2.
Mol Cell Endocrinol 247: 150-165, 2006
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Tao R-H, Kawate H, Ohnaka K, Ishizuka M, Hagiwara H, Takayanagi R:
Opposite effects of alternative TZF spliced variants on androgen receptor.
Biochem Biophys Res Commun 341: 515-521, 2006
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Kawate H, Wu Y, Ohnaka K, Tao R-H, Nakamura K-I, Okabe T, Yanase T, Nawata H, Takayanagi R:
Impaired nuclear translocation, nuclear matrix targeting and intranuclear mobility of mutant androgen receptors carrying amino acid substitutions in the DNA-binding domain derived from androgen insensitivity syndrome patients.
J Clin Endocrinol Metab 90: 6162-6169, 2005
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Chen G, Nomura M, Morinaga H, Matsubara E, Okabe T, Goto K, Yanase T, Zheng H, Lu J, Nawata H:
Modulation of androgen receptor transactivation by FoxH1: A newly identified androgen receptor corepressor.
J Biol Chem 280: 36355-36363, 2005
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Nicol CJ, Adachi M, Akiyama TE, Gonzalez FJ:
PPARgamma in endothelial cells influences high fat diet-induced hypertension.
Am J Hypertens 18: 549-556, 2005
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Ishizuka M, Kawate H, Takayanagi R, Ohshima H, Tao R-H, Hagiwara H:
A zinc finger protein TZF is a novel corepressor of androgen receptor.
Biochem Biophys Res Commun 331: 1025-1031, 2005
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Fan W, Yanase T, Nomura M, Okabe T, Goto K, Sato T, Kawano H, Kato S, Nawata H:
Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion.
Diabetes 54: 1000-1008, 2005
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Ashida K, Goto K, Zhao Y, Okabe T, Yanase T, Takayanagi R, Nomura M, Nawata H:
Dehydroepiandrosterone negatively regulates the p38 mitogen-activated protein kinase pathway by a novel mitogen-activated protein kinase phosphatase.
Biochem Biophys Acta 1728: 84-94, 2005
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Kawate H, Wu Y, Ohnaka K, Nawata H, Takayanagi R:
Tob proteins suppress steroid hormone receptor-mediated transcriptional activation.
Mol Cell Endocrinol 230: 77-86, 2005
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野村政壽:
内分泌疾患患者へのアプローチ
「内科学」金澤一郎、北原光夫、山口徹、小俣政男 編集：P.2079-83 医学書院、東京、2006
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坂本竜一, 野村政壽:
「専門医を目指すケース・メソッド・アプローチ 内分泌疾患」
肥塚直美 編集：p.210-221 日本医事新報社、東京、2007
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野村政壽:
ミトコンドリアと糖尿病
「コメディカル・研修医・一般臨床医のための糖尿病治療ハンドブック」永淵正法 編集：p25-27 医学出版、東京、2009
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| 最近の主な論文・日本語総説 |
2011/5/17 更新 |
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Sada E, Abe Y, Ohba R, Tachikawa Y, Nagasawa E, Shiratsuchi M, Takayanagi R:
Vitamin K2 modulates differentiation and apoptosis of bith myeloid and erythroid lineages.
Eur J Haematol 85: 538-548, 2010
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Ohtsuka R, Abe Y, Sada E, Kiyasu J, Ashikari A, Shiratsuchi M, Nishimura J, Takayanagi R, Ohshima K:
Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?
Intern Med 48: 471-474, 2009
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Abe Y, Ito T, Baba E, Nagafuji K, Kawabe K, Choi I, Arita Y, Miyamoto T, Teshima T, Nakano S, Harada M:
Nonmyeloablative allogeneic hematopoietic stem cell transplantation as immunotherapy for pancreatic cancer.
Pancreas 38: 815-819, 2009
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Miyashita K, Fujii K, Yamada Y, Hattori H, Taguchi K, Yamanaka T, Yoshida MA, Okamura J, Oda S, Muta K, Nawata H, Takayanagi R, Uike N:
Frequent microsatellite instability in non-Hodgkin lymphomas irresponsive to chemotherapy.
Leukemia Research 32: 1183-1195, 2008
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Podack ER, Deyev V, Shiratsuchi M:
Pore formers of the immune system.
Adv Exp Med Biol 598: 325-341, 2007
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Sarakul O, Vattanaviboon P, Wilairat P, Fucharoen S, Abe Y, Muta K:
Inhibition of alpha-globin gene expression by RNAi.
Biochem Biophys Res Commun 369: 935-8, 2008
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Masaki S, Ohtsuka R, Abe Y, Muta K, Umemura T:
Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis.
Biochem Biophys Res Commun 364: 509-514, 2007
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Ohtsuka R, Abe Y, Fujii T, Yamamoto M, Nishimura J, Takayanagi R, Muta K:
Mortalin is a novel mediator of erythropoietin signaling.
Eur J Haematol 79: 114-125, 2007
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Tachikawa Y, Matsushima T, Abe Y, Sakano S, Yamamoto M, Nishimura J, Nawata H, Takayanagi R, Muta K:
Pivotal role of Notch signaling in regulation of erythroid maturation and proliferation.
Eur J Haematol 77: 273-281, 2006
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Nakashima Y, Tagawa H, Suzuki R, Karnan S, Karube K, Ohshima K, Muta K, Nawata H, Morishima Y, Nakamura S, Seto M:
Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type.
Genes Chromosomes Cancer 44: 247-255, 2005
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Nagasawa E, Abe Y, Nishimura J, Yanase T, Nawata H, Muta K:
Pivotal role of peroxisome proliferator-activated receptor gamma (PPARγ) in regulation of erythroid progenitor cell proliferation and differentiation.
Exp Hematol 33: 857-864, 2005
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Sae-Ung N, Matsushima T, Choi I, Abe Y, Winichagoon P, Fucharoen S, Nawata H, Muta K:
Role of NF-κB in regulation of apoptosis of erythroid progenitor cells.
Eur J Haematol 74: 315-323, 2005
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Zhang M, Abe Y, Matsushima T, Nishimura J, Nawata H, Muta K:
Selective cyclooxygenase 2 inhibitor NS-398 induces apoptosis in myeloma cells via a Bcl-2 independent pathway.
Leuk Lymphoma 46: 425-433, 2005
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Muta K, Ohshima K, Abe Y, Uike N, Choi I, Matsushima T, Nishimura J, Kikuchi M, Nakashima M, Watanabe T, Nawata H:
Expression of human tumor-associated antigen RCAS1 in adult T-cell leukemia/lymphoma.
Int J Hematol 79: 340-344, 2004
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Shiokawa S, Matsushima T, Choi I, Abe Y, Shiratsuchi M, Suehiro Y, Muta K, Ohshima K, Nishimura J:
Re-entry of tumor B cells into the cycle of somatic mutation and isotype switching in follicular lymphoma.
Br J Haematol 120: 492-495, 2003
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Abe Y, Ohshima K, Nakashima M, Hara K, Matsushima T, Choi I, Nishimura J, Kikuchi M, Nawata H, Watanabe T, Muta K:
Expression of apoptosis-associated protein RCAS1 in macrophages of histiocytic necrotizing lymphadenitis.
Int J Hematol 77: 359-363, 2003
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Minami R, Muta K, Umemura T, Motomura S, Abe Y, Nishimura J, Nawata H:
p16(INK4a) induces differentiation and apoptosis in erythroid lineage cells.
Exp Hematol 31: 355-362, 2003
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Paiboonsukwong K, Choi I, Matsushima T, Abe Y, Nishimura J, Winichagoon P, Fucharoen S, Nawata H, Muta K:
The signaling pathways of erythropoietin and interferon-γ differ in preventing the apoptosis of mature erythroid progenitor cells.
Int J Hematol 78: 421-428, 2003
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Abe Y, Choi I, Matsushima T, Nishimura J, Inaba S, Nawata H, Muta K:
Hemophagocytic syndrome: a rare complication of allogeneic nonmyeloablative hematopoietic stem cell transplantation.
Bone Marrow Transplant 29: 799-801, 2002
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Shiratsuchi M, Muta K, Abe Y, Motomura S, Taguchi F, Takatsuki H, Uike N, Umemura T, Nawata H, Nishimura J:
Clinical significance of telomerase activity in multiple myeloma.
Cancer 94: 2232-2238, 2002
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Matsushima T, Nakashima M, Oshima K, Abe Y, Nishimura J, Nawata H, Watanabe T, Muta K:
Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cells.
Blood 98: 313-321, 2001
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Choi I, Muta K, Wickrema A, Krantz SB, Nishimura J, Nawata H:
Interferon gamma delays apoptosis of mature erythroid progenitor cells in the absence of erythropoietin.
Blood 95: 3742-3749, 2000
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安部康信, 大島孝一:
EBV関連リンパ腫をどう理解するか
症例検討を通して学ぶ悪性リンパ腫診療の実際−リンフォーマ井戸端会議から学んだこと−: メディカルレビュー社; 97-102, 2010
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牟田耕一郎, 安部康信:
サラセミア
専門医のための薬物療法Q＆A: 中外医学社; 92-98, 2007
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白土基明, 牟田耕一郎:
先天性疾患における輸血依存性鉄過剰症の病態
Iron Overloadと鉄キレート療法: メディカルレビュー社; 117-122, 2007
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| 最近の主な論文・日本語総説 |
2012/5/7 更新 |
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Miyazaki M, Kato M, Tanaka M, Tanaka K, Takao S, Kohjima M, Ito T, Enjoji M, Nakamuta M, Kotoh K, Takayanagi R:
Antithrombin III injection via the portal vein suppresses liver damage
World J Gastroenterol 18: 1884-1891, 2012
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Nakamuta M, Kohjima M:
Lipid metabolism-related gene expression in hepatocellular carcinoma.
Nihon Shokakibyo Gakkai Zasshi 109: 555-562, 2012
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Kotoh K, Fukushima M, Horikawa Y, Yamashita S, Kohjima M, Nakamuta M, Enjoji M:
Serum albumin is present at higher levels in alcoholic liver cirrhosis as compared to HCV-related cirrhosis
EXPERIMENTAL AND THERAPEUTIC MEDICINE 3: 72-75, 2012
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Miyazaki M, Kato M, Tanaka K, Tanaka M, Kohjima M, Nakamura K, Enjoji M, Nakamuta M, Kotoh K, Takayanagi R:
Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism
Mol Med Report 5: 729-733. 2012
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Miyazaki M, Kato M, Tanaka M, Tanaka K, Takao S, Kohjima M, Ito T, Enjoji M, Nakamuta M, Kotoh K, Takayanagi R:
Contrast-enhanced ultrasonography using Sonazoid to evaluate changes in hepatic hemodynamics in acute liver injury.
J Gastroenterol Hepatol 26: 1749-1756, 2011
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Miyazaki M, Tanaka M, Ueda A, Yoshimoto T, Kato M, Nakamuta M, Kotoh K, Takayanagi R:
Acute liver failure caused by drug-induced hypersensitivity syndrome associated with hyperferritinemia.
World J Gastroenterol 17: 4928-4931, 2011
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Higuchi N, Kato M, Tanaka M, Miyazaki M, Takao S, Kohjima M, Kotoh K, Enjoji M, Nakamuta M, Takayanagi R:
Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease
EXPERIMENTAL AND THERAPEUTIC MEDICINE 21077-21081, 2011
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Tanaka K, Nakasha A, Miyazaki M, Takao S, Higuchi N, Tanaka M, Tanaka Y, Kato M, Kotoh K, Takayanagi R, Aishima S:
A Case of Hepatocellular Carcinoma with Respiratory Failure Caused by Widespread Tumor Microemboli
Fukuoka Igaku Zasshi 102: 298-302, 2011
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Nakamuta M, Fujino T, Yada R, Aoyagi Y, Yasutake K, Kohjima M, Fukuizumi K, Yoshimoto T, Harada N, Yada M, Kato M, Kotoh K, Taketomi A. Maehara Y, Nakashima M, Enjoji M:
Expression profiles of genes associated with viral entry in HCV-infected human liver.
J Med Virol 83: 921-927, 2011
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Higuchi N, Kato M, Miyazaki M, Tanaka M, Kohjima M, Ito T, Nakamuta M, Enjoji M, Kotoh K, Takayanagi R:
Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver.
J Cell Biochem 112: 30-38, 2011
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Miyazaki M, Kato M, Tanaka M, Takayanagi R:
High-density lipoprotein cholesterol improves the model for end-stage liver disease scoring system for prognostic prediction of acute liver failure.
Scand J Gastroenterol 45: 506-508, 2010
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Kotoh K, Kato M, Kohjima M, Nakamuta M, Enjoji M:
A new treatment strategy for acute liver failure.
World J Hepatol 2: 395-400, 2010
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Gotoh K, Tanaka Y, Nishikimi A, Nakamura R, Yamada H, Maeda N, Ishikawa T, Hoshino K, Uruno T, Cao Q, Higashi S, Kawaguchi Y, Enjoji M, Takayanagi R, Kaisho T, Yoshikai Y, Fukui Y:
Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.
J Exp Med 207: 721-730, 2010
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Nakamuta M, Fujino T, Yada R, Yasutake K, Yoshimoto T, Harada N, Yada M, Higuchi N, Kato M, Kohjima M, Taketomi A, Maehara Y, Nishinakagawa T, Machida K, Matsunaga K, Nakashima M, Kotoh K, Enjoji M:
Therapeutic effect of bezafibrate against biliary damage: a study of phospholipid secretion via the PPARalpha-MDR3 pathway.
Int J Clin Pharmacol Ther 48: 22-28, 2010
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Kohjima M, Sun Y, Chan L:
Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse model.
Endocrinology 151: 1532-1540, 2010
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Yada M, Masumoto A, Yamashita N, Motomura K, Koyanagi T, Sakamoto S:
Immediate virological response predicts the success of short-term peg-interferon monotherapy for chronic hepatitis C.
World J Gastroenterol 16: 1506-1511, 2010
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Enjoji M, Machida K, Kohjima M, Kato M, Kotoh K, Matsunaga K, Nakashima M, Nakamuta M:
NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease.
Lipids Health Dis 9: 29, 2010
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Miyazaki M, Higuchi N,Tanaka M, Ueda A, Nagata S, Ikegami T, Kato M, Soejima Y, Taketomi A, Takayanagi R:
Living donor liver transplantation for acute liver failure caused by acute fatty liver of pregnancy
American J Case Rep 11: 126-129, 2010
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Enjoji M, Nakamuta M:
Is the control of dietary cholesterol intake sufficiently effective to ameliorate nonalcoholic fatty liver disease?
World J Gastroenterol 16: 800-803, 2010
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Kotoh K, Takayanagi R:
A new treatment strategy for fulminant hepatic failure with transcatheter arterial steroid injection therapy.
Fukuoka Igaku Zasshi 101: 109-118, 2010
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Nakamuta M, Yada R, Fujino T, Yada M, Higuchi N, Tanaka M, Miyazaki M, Kohjima M, Kato M, Yoshimoto T, Harada N, Taketomi A, Maehara Y, Koga M, Nishinakagawa T, Nakashima M, Kotoh K, Enjoji M:
Changes in the expression of cholesterol metabolism-associated genes in HCV-infected liver: a novel target for therapy?
Int J Mol Med 24: 825-828, 2009
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Enjoji M, Yada R, Fujino T, Yoshimoto T, Yada M, Harada N, Higuchi N, Kato M, Kohjima M, Taketomi A, Maehara Y, Nakashima M, Kotoh K, Nakamuta M:
The state of cholesterol metabolism in the liver of patients with primary biliary cirrhosis: the role of MDR3 expression.
Hepatol Int 3: 490-496, 2009
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Nakamuta M, Fujino T, Yada R, Yada M, Yasutake K, Yoshimoto T, Harada N, Higuchi N, Kato M, Kohjima M, Taketomi A, Maehara Y, Nakashima M, Kotoh K, Enjoji M:
Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease.
Int J Mol Med 23: 603-608, 2009
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Kohjima M, Enjoji M, Higuchi N, Kato M, Kotoh K, Nakashima M, Nakamuta M:
The effects of unsaturated fatty acids on lipid metabolism in HepG2 cells.
In Vitro Cell Dev Biol Anim 45: 6-9, 2009
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中牟田誠, 国府島庸之:
肝胆膵疾患と栄養量法の最前線 脂質代謝異常
肝胆膵 66: 399-406, 2011
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中牟田誠, 国府島庸之:
ウィルス肝炎診療の変貌：近づく疾患克服 メトフォルミン・ピオグリタゾン
肝胆膵 62: 355-361, 2011
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中牟田誠, 国府島庸之:
肝発癌・進展とインスリン抵抗性 肝細胞癌部と非癌部におけるインスリンシグナル関連・脂質代謝関連遺伝子の発現
消化器内科 52: 302-307, 2011
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中牟田誠:
内科医のための肝臓・胆道系機能異常の診断と治療ーウィルス肝炎からNASH・肝臓がんまでー 自己免疫性肝炎
診断と治療 98: 807-811, 2010
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中牟田誠, 国府島庸之:
C型肝炎ウィルスの増殖・感染メカニズムにおける脂質代謝・インスリンシグナルの重要性
消化器内科 51: 619-626, 2010
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杉本理恵, 奥村幸彦, 船越顕博:
高齢者肝細胞癌の特徴、治療、予後と栄養の関係
消化と吸収 33: 286-293, 2010
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| 最近の主な論文・日本語総説 |
2012/5/7 更新 |
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Hendarto H, Inoguchi T, Maeda Y, Ikeda N, Zheng J, Takei R, Yokomizo H, Hirata E, Sonoda N, Takayanagi R:
GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases.
Metabolism. 2012 May 1. [Epub ahead of print]
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Kimura S, Inoguchi T, Yokomizo H, Maeda Y, Sonoda N, Takayanagi R:
Randomized comparison of pitavastatin and pravastatin treatment on the reduction of urinary albumin in patients with type 2 diabetic nephropathy.
Diabetes Obes Metab. 2012 Jan 23 [Epub ahead of print]
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Inoue T, Kobayashi K, Inoguchi T, Sonoda N, Fujii M, Maeda Y, Fujimura Y, Miura D, Hirano K, Takayanagi R:
Reduced expression of adipose triglyceride lipase enhances tumor necrosis factor α-induced intercellular adhesion molecule-1 expression in human aortic endothelial cells via protein kinase c-dependent activation of nuclear factor-κB.
J Biol Chem 286: 32045-32053, 2011
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Ikeda N, Inoguchi T, Sonoda N, Fujii M, Takei R, Hirata E, Yokomizo H, Zheng J, Maeda Y, Kobayashi K, Takayanagi R:
Biliverdin protects against the deterioration of glucose tolerance in db/db mice.
Diabetologia 54: 2183-2191, 2011
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Maeda Y, Inoguchi T, Takei R, Sawada F, Sasaki S, Fujii M, Kobayashi K, Urata H, Nishiyama A, Takayanagi R:
Inhibition of chymase protects against diabetes-induced oxidative stress and renal dysfunction in hamsters.
Am J Physiol Renal Physiol 299: F1328-1338, 2010
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Fujii M, Inoguchi T, Sasaki S, Maeda Y, Zheng J, Kobayashi K, Takayanagi R.:
Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase.
Kidney Int 78: 905-919, 2010
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Kobayashi K, Inoguchi T, Maeda Y, Nakashima N, Kuwano A, Eto E, Ueno N, Sasaki S, Sawada F, Fujii M, Matoba Y, Sumiyoshi S, Kawate H, Takayanagi R:
The Lack of the C-terminal Domain of Adipose Triglyceride Lipase Causes Neutral Lipid Storage Disease through Impaired Interactions with Lipid Droplets.
J Clin Endocrinol Metab 93: 2877-2884, 2008
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Sawada F, Inoguchi T, Tsubouchi H, Sasaki S, Fujii M, Maeda Y, Morinaga H, Nomura M, Kobayashi K, Takayanagi R:
Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic β-cell line, MIN6.
Metabolism 57: 1038-1045, 2008
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Matoba Y, Inoguchi T, Nasu S, Suzuki S, Yanase T, Nawata H, Takayanagi R:
Optimal cut points of waist circumference for the clinical diagnosis of metabolic syndrome in the Japanese population.
Diabetes Care 31: 590-592, 2008
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Inoguchi T, Sasaki S, Kobayashi K, Takayanagi R, Yamada T:
Relationship between Gilbert syndrome and prevalence of vascular complications in patients with diabetes.
JAMA 298: 1398-1400, 2007
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Fujii M, Inoguchi T, Maeda Y, Sasaki S, Sawada F, Saito R, Kobayashi K, Sumimoto H, Takayanagi R:
Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice.
Kidney Int 72: 473-480, 2007
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Sasaki S, Inoguchi T, Muta K, Abe Y, Zhang M, Hiasa K, Egashira K, Sonoda N, Kobayashi K, Takayanagi R, Nawata H:
Therapeutic angiogenesis by ex vivo expanded erythroid progenitor cells.
Am J Physiol Heart Circ Physiol 292: H657-665, 2007
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Inoguchi T, Nawata H:
NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive β-cell dysfunction and metabolic syndrome.
Curr Drug Targets 6: 495-501, 2005
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Tsubouchi H, Inoguchi T, Inuo M, Kakimoto M, Sonta T, Sonoda N, Sasaki S, Kobayashi K, Sumimoto H, Nawata H:
Sulfonylurea as well as elevated glucose levels stimulate reactive oxygen species production in the pancreatic β-cell line, MIN6-a role of NAD(P)H oxidase in β-cells.
Biochem Biophys Res Commun 326: 60-65, 2005
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Sato N, Kobayashi K, Inoguchi T, Sonoda N, Imamura M, Sekiguchi N, Nakashima N, Nawata H:
Adenovirus-mediated high expression of resistin causes dyslipidemia in mice.
Endocrinology 146: 273-279, 2005
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Sonta T, Inoguchi T, Matsumoto S, Yasukawa K, Inuo M, Tsubouchi H, Sonoda N, Kobayashi K, Utsumi H, Nawata H:
In vivo imaging of oxidative stress in the kidney of diabetic mice and its normalization by angiotensin II type 1 receptor blocker
Biochem Biophys Res Commun 330: 415-422, 2005
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Tsubouchi H, Inoguchi T, Sonta T, Sato N, Sekiguchi N, Kobayashi K, Sumimoto H, Utsumi H, Nawata H:
Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement
Free Radic Biol Med 15: 444-452, 2005
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Sonta T, Inoguchi T, Tsubouchi H, Sekiguchi N, Kobayashi K, Matsumoto S, Utsumi H, Nawata H:
Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity.
Free Radic Biol Med 37: 115-123, 2004
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Inoguchi T, Sonta T, Tsubouchi H, Etoh T, Kakimoto M, Sonoda N, Sato N, Sekiguchi N, Kobayashi K., Sumimoto H, Utsumi H, Nawata H:
Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes : Role of vascular NAD(P)H oxidase.
J Am Soc Nephrol 143: 227-232, 2003
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Inoguchi T, Tsubouchi H, Etoh T, Kakimoto M, Sonta T, Utsumi H, Sumimoto H, Yu HY, Sonoda N, Inuo M, Sato N, Sekiguchi N, Kobayashi K, Nawata H:
A possible target of antioxidative therapy for diabetic vascular complications-vascular NAD(P)H oxidase.
Curr Med Chem 1017: 1759-1764, 2003
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Etoh T, Inoguchi T, Kakimoto M, Sonoda N, Kobayashi K, Kuroda J, Sumimoto H, Nawata H:
Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment.
Diabetologia 46: 1428-1437, 2003
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Imamura M, Inoguchi T, Ikuyama S, Taniguchi S, Kobayashi K, Nakashima N, Nawata H:
ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts.
Am J Physiol Endocrinol Metab 283: 775-783, 2002
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Kakimoto M, Inoguchi T, Sonta T, Yu HY, Imamura M., Etoh T, Hashimoto T, Nawata H:
Accumulation of 8-hydroxy-2'-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats.
Diabetes 51: 1588-1595, 2002
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Yu HY, Inoguchi T, Kakimoto M, Nakashima N, Imamura M, Hashimoto T, Umeda F, Nawata H:
Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells.
Diabetologia 44: 614-620, 2001
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Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano H, Utsumi H, Nawata H:
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells.
Diabetes 49: 1939-1945, 2000
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Ono Y, Umeda F, Kunisaki M, Sekiguchi N, Hashimoto T, Nawata H:
Effect of high glucose concentrations on prostacyclin-stimulating factor mRNA expression in cultured aortic smooth muscle cells
Diabetologia 41: 134-140, 1998
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Kuroki T, Inoguchi T, Umeda F, Nawata H:
Effect of eicosapentaenoic acid on glucose-induced diacylglycerol synthesis in cultured bovine aortic endothelial cells.
Biochem Biophys Res Commun 247: 473-477, 1998
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Kuroki T, Inoguchi T, Umeda F, Ueda F, Nawata H:
High glucose induced alteration of gap junction permeability and phosphorylation of connexin-43 in cultured aortic smooth muscle cells.
Diabetes 47: 931-936, 1998
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Sano T, Umeda F, Hashimoto T, Nawata H, Utsumi H:
Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes.
Diabetologia 41: 1355-1360, 1998
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| 最近の主な論文・日本語総説 |
2012/5/7 更新 |
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Igarashi H, Ito T, Hisano T, Fujimor N, Niina Y, Yasuda M, Kaku T, Matsuo S, Oono T, Yoshinaga M, Sakai H, Takayanagi R:
Paclitaxel-Based Chemotherapy for Advanced Pancreatic Cancer after Gemcitabine-Based Therapy Failure: a case series of 5 patients.
Case Rep Oncol 4 :534-541, 2011
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Fujimori N, Oono T, Igarashi H, Ito T, Nakamura T, Uchida M, Coy DH, Jensen RT, Takayanagi R:
Vasoactive intestinal peptide reduces oxidative stress in pancreatic acinar cells through the inhibition of NADPH oxidase.
Peptides 32: 2067-2076, 2011
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Igarashi H, Fujimori N, Ito T, Nakamura T, Oono T, Nakamura K, Suzuki K, Jensen RT, Takayanagi R:
Vasoactive Intestinal Peptide (VIP) and VIP Receptors-Elucidation of Structure and Function for Therapeutic Applications
Int J Clin Med 2: 500-508, 2011
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Nakamura T, Ito T, Oono T, Igarashi H, Fujimori N, Uchida M, Niina Y, Yasuda M, Suzuki K, Takayanagi R:
Bacterial DNA Promotes Proliferation of Rat Pancreatic Stellate Cells Thorough Toll-Like Receptor 9: Potential Mechanisms for Bacterially Induced Fibrosis.
Pancreas 40: 823-831, 2011
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Ito T, Nakamura T, Fujimori N, Niina Y, Igarashi H, Oono T, Uchida M, Kawabe K, Takayanagi R, Nishimori I, Otsuki M, Shimosegawa T:
Characteristics of Pancreatic Diabetes in Patients with Autoimmune Pancreatitis.
J Dig Dis 12: 210-216, 2011
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Yao JC, Ito T, berg K:
Advances in pancreatic neuroendocrine tumor treatment. Correspondence; Baseline factors affecting blood glucose in the phase III study of everolimus among pancreatic neuroendocrine tumors.
N Engl J Med 364: 1871-1875, 2011
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Fujimori N, Igarashi H, Ito T:
Acute obstructive suppurative pancreatic ductitis.
Clin Gastroenterol Hepatol 9: A28, 2011
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Kawabe K, Ito T, Okano S:
Simultaneous double cancers in the pancreas.
Clin Gastroenterol Hepatol 9: A40, 2011
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Yao JC, Shah MH, Ito T, Bohas CL, Wolin EM, Van Cutsem E, Hobday TJ, Okusaka T, Capdevila J, de Vries EG, Tomassetti P, Pavel ME, Hoosen S, Haas T, Lincy J, Lebwohl D, Öberg K; RAD001 in Advanced Neuroendocrine Tumors, Third Trial (RADIANT-3) Study Group:
Everolimus for Advanced Pancreatic Neuroendocrine Tumors.
N Engl J Med 364: 514-523, 2011
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Okusaka T, Furuse J, Funakoshi A, Ioka T, Yamao K, Ohkawa S, Boku N, Komatsu Y, Nakamori S, Iguchi H, Ito T, Nakagawa K, Nakachi K:
Phase II study of erlotinib plus gemcitabine in Japanese patients with unresectable pancreatic cancer.
Cancer Sci 102: 425-431, 2011
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Moody TW, Ito T, Osefo N, Jensen RT:
VIP and PACAP: recent insights into their functions/roles in physiology and disease from molecular and genetic studies.
Curr Opin Endocrinol Diabetes Obes 18: 61-67, 2011
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Ojeaburu JV, Ito T, Crafa P, Bordi C, Jensen RT:
Mechanism of Acid Hypersecretion Post-Curative Gastrinoma Resection.
Dig Dis Sci 56: 139-154, 2011
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Ito T, Igarashi1 H, Niina1 Y, Hijioka1 M, Matsuo S, Shimokawa Y, Yonekura M, Nakamura K, Takayanagi R:
Management of Pain in Chronic Pancreatitis with Home Elemental Diet Ingestion.
JOP 11: 648-649, 2010
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Ito T, Jensen RT:
Association of Long-term Proton Pump Inhibitor Therapy with Bone Fractures and effects on Absorption of Calcium, Vitamin B12, Iron, and Magnesium.
Current Gastroenterol Reports 12: 448-457, 2010
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Tamura K, Nishimori I, Ito T, Yamasaki I, Igarashi H, Shuin T:
Diagnosis and management of pancreatic neuroendocrine tumor in von Hippel-Lindau disease.
World J Gastroenterol 36: 4515-4518, 2010
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Igarashi H, Ito T, Takayanagi R:
The new concept of therapeutic strategy for neuroendocrine tumors: the important information from a case report of gastrinoma.
Internal Med 49: 1839-40, 2010
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Nakamura K, Akiho H, Ochiai T, Motomura Y, Higuchi N, Okamoto R, Matsui N, Yasuda D, Akahoshi K, Kabemura T, Ihara E, Harada N, Ito T, Takayanagi R:
Randomized controlled trial: roxatidine vs omeprazole for non-erosive reflux disease.
Hepatogastroenterology 57: 497-500, 2010
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Ito T, Otsuki M, Igarashi H, Kihara Y, Kawabe K, Nakamura T, Fujimori N, Oono T, Takayanagi R, Shimosegawa T:
Epidemiological Study of Pancreatic Diabetes in Japan in 2005 : A Nationwide Study.
Pancreas 39: 829-835, 2010
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Fujimori N, Nakamura T, Oono T, Igarashi H, Takahata S, Nakamura M, Tanaka M, Hayashi A, Aishima S, Ishigami S, Ogoshi K, Ito T, Takayanagi R:
Adenocarcinoma involving the whole pancreas with multiple pancreatic masses.
Intern Med 49: 1527-1532, 2010
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Shimosegawa T, Kataoka K, Kamisawa T, Miyakawa H, Ohara H, Ito T, Naruse S, Sata N, Suda K, Hirota M, Takeyama Y, Shiratori K, Hatori T, Otsuki M, Atomi Y, Sugano K, Tanaka M:
The revised Japanese clinical diagnostic criteria for chronic pancreatitis.
J Gastroenterol 45: 584-591, 2010
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Ito T, Sasano H, Tanaka M, Osamura RY, Sasaki I, Kimura W, Takano K, Obara T, Ishibashi M, Nakao K, Doi R, Shimatsu A, Nishida T, Komoto I, Hirata Y, Nakamura K, Igarashi H, Jensen RT, Wiedenmann B, Imamura M:
Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan.
J Gastroenterol 45: 234-243, 2010
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Ito T, Jensen RT:
Primary hepatic gastrinoma: an unusual case of zollinger-ellison syndrome.
Gastroenterol Hepatol (N Y) 6: 57-59, 2010
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Igarashi H, Ito T, Yoshinaga M, Oono T, Sakai H, Takayanagi R:
Acetaminophen-induced acute pancreatitis. A case report.
JOP 10: 550-553, 2009
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Kawabe K, Ito T, Igarashi H, Takayanagi R:
The current managements of pancreatic diabetes in Japan.
Clin J Gastroenterol 2: 1-8, 2009
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Kamisawa T, Shimosegawa T, Okazaki K, Nishino T, Watanabe H, Kanno A, Okumura F, Nishikawa T, Kobayashi K, Ichiya T, Takatori H, Yamakita K, Kubota K, Hamano H, Okamura K, Hirano K, Ito T, Ko SB, Omata M:
Standard steroid treatment for autoimmune pancreatitis.
Gut 58: 1504-1507, 2009
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Okazaki K, Kawa S, Kamisawa T, Ito T, Inui K, Irie H, Irisawa A, Kubo K, Notohara K, Hasebe O, Fujinaga Y, Ohara H, Tanaka S, Nishino T, Nishimori I, Nishiyama T, Suda K, Shiratori K, Shimosegawa T, Tanaka M:
Japanese clinical guidelines for autoimmune pancreatitis.
Pancreas 38: 849-866, 2009.
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Igarashi H, Ito T, Kuwano-Kojima M, Takayanagi R, Coy DH, Jensen RT:
Involvement of VPAC1 and VPAC2 receptors for increasing in local pancreatic blood flow in anaesthetized rats.
Pancreas 37: 236-238, 2008
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Igarashi H, Ito T, Kawabe K, Hisano T, Arita Y, Kaku T , Takayanagi R:
Chemoradiotherapy with twice-weekly administration of low-dose gemcitabine for locally advanced pancreatic cancer.
World J Gastroenterol 14: 5311-5315, 2008
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Nakamura T, Ito T, Abe Y, Izutsu K, Gibo J, Itaba S, Kawabe K, Oono T, Igarashi H, Yamaguchi K, Ohshima K, Takayanagi R:
Primary pancreatic low-grade mucosa-associated lymphoid tissue lymphoma presenting with multiple masses.
Clin J Gastroenterol 1: 168-73, 2008
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Ito T:
Can measurement of chemokines become useful biological and functional markers of early-stage chronic pancreatitis?
J Gastroenterol 42: 72-77, 2007
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Ito T, Nishimori I, Inoue N, Kawabe K, Gibo J, Arita Y, Okazaki K, Takayanagi R, Otsuki M:
Treatment for autoimmune pancreatitis: consensus on the treatment for patients with autoimmune pancreatitis in Japan.
J Gastroenterol 42: 50-58, 2007
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Ito T, Otsuki M, Itoi T, Shimosegawa T, Funakoshi A, Shiratori K, Naruse S, Kuroda Y; Research Committee of Intractable Diseases of the Pancreas:
Pancreatic diabetes in a follow-up survey of chronic pancreatitis in Japan.
J Gastroenterol 42: 291-297, 2007
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Ito T, Tanaka M, Sasano H, Osamura YR, Sasaki I, Kimura W, Takano K, Obara T, Ishibashi M, Nakao K, Doi R, Shimatsu A, Nishida T, Komoto I, Hirata Y, Imamura M, Kawabe K, Nakamura K; Neuroendocrine Tumor Workshop of Japan:
Preliminary results of a Japanese nationwide survey of neuroendocrine gastrointestinal tumors.
J Gastroenterol 42: 497-600, 2007
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Ito T, Kawabe K, Arita Y, Hisano T, Igarashi H, Funakoshi A, Sumii T, Yamanaka T, Takayanagi R:
Evaluation of pancreatic endocrine and exocrine function in patients with autoimmune pancreatitis.
Pancreas 34: 254-259, 2007
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Ito T, Nishimori I, Okazaki K, Kawa S, Koizumi M, Kamisawa T, Otsuki M:
Other organ involvement in autoimmune pancreatitis.
The Korean Journal of Pancreas and Biliary Tract 12:100-101, 2007
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Igarashi H, Ito T, Yoshinaga M, Kodama M, Hayashi H, Sakai H, Kawabe K, Takayanagi R:
Successful management of multiple liver metastases from pancreatic neuroendocrine tumor by hepatic arterial administration of cisplatin powder.
Pancreas 35: 288-290, 2007
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Kojima M, Ito T, Oono T, Hisano T, Igarashi H, Arita Y, Kawabe K, Coy DH, Jensen RT, Nawata H:
VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production.
Pancreas 30: 62-70, 2005
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Gibo J, Ito T, Kawabe K, Hisano T, Inoue M, Fujimori N, Oono T, Arita Y, Nawata H:
Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity.
Lab Invest 85: 75-89, 2005
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Zhao H, Ito T, Gibo J, Kawabe K, Oono T, Kaku T, Arita Y, Zhao Q, Usui M, Egashira K, Nawata H:
Anti-monocyte chemoattractant protein-1 gene therapy attenuates experimental chronic pancreatitis induced by dibutyltin dichloride in rats.
Gut 54: 1759-67, 2005
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五十嵐久人, 藤森尚, 伊藤鉄英:
膵腫瘍：診断と治療の進歩 膵内分泌腫瘍 疫学・症候・診断
日本内科学会雑誌 101(1): 100-108, 2012
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下瀬川 徹, 伊藤 鉄英, 明石 隆吉, 五十嵐 久人, 他: 厚生労働省科学研究費補助金難治性疾患克服研究事業難治性膵疾患に関する調査研究班
急性膵炎における初期診療のコンセンサス 改訂第3版
膵臓 26(6): 651-683, 2011
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下瀬川徹, 伊藤鉄英, 中村太一, 他: 厚生労働省科学研究費補助金難治性疾患克服研究事業難治性膵疾患に関する調査研究班
慢性膵炎の断酒・生活指導指針
膵臓 25(6): 617-681, 2010
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伊藤鉄英, 中村太一, 藤森 尚, 大野隆真, 安田幹彦, 新名雄介, 内田匡彦, 五十嵐久人, 高柳涼一:
膵炎：診断と治療の進歩 慢性膵炎の治療
日本内科学会雑誌 99(1)：56-61, 2010
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| 最近の主な論文・日本語総説 |
2012/5/7 更新 |
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Itaba S, Iboshi Y, Nakamura K, Ogino H, Sumida Y, Aso A, Yoshinaga S, Akiho H, Igarashi H, Kato M, Kotoh K, Ito T, Takayanagi R:
Low-frequency of bacteremia after endoscopic submucosal dissection of the stomach.
Dig Endosc 23: 69-72, 2011
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Goto A, Hirahashi M, Osada M, Nakamura K, Yao T, Tsuneyoshi M, Takayanagi R, Oda Y:
Aberrant activation-induced cytidine deaminase expression is associated with mucosal intestinalization in the early stage of gastric cancer.
Virchows Arch 458: 717-724, 2011
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Kanayama K, Nakamura K, Ogino H, Sumida Y, Ihara E, Akiho H, Takayanagi R:
Th1 responses are more susceptible to infliximab-mediated immunosuppression than Th17 responses.
Dig Dis Sci 56: 3525-3533, 2011
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Ogino H, Nakamura K, Iwasa T, Ihara E, Akiho H, Motomura Y, Akahoshi K, Igarashi H, Kato M, Kotoh K, Ito T, Takayanagi R:
Regulatory T Cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model.
J Gastroenterol 47: 366-376, 2012
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Akiho H, Nakamura K:
Daikenchuto ameliorated muscle hypercontractility in a murine T-cell-mediated persistent gut motor dysfunction model.
Digestion 83: 173-179, 2011
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Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R:
CD4+CD25+ regulatory T cells suppress Th17-responses in an experimental colitis model.
Dig Dis Sci 56: 376-386, 2011
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Iwasa T, Nakamura K, Ogino H, Itaba S, Akiho H, Okamoto R, Iboshi Y, Aso A, Murao H, Kanayama K, Ito T, Takayanagi R:
Multiple ulcers in the small and large intestines occurred during tocilizumab therapy for rheumatoid arthritis.
Endoscopy 43: 70-72, 2011
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Akahoshi K, Honda K, Motomura Y, Kubokawa M, Okamoto R, Osoegawa T, Nakama N, Kashiwabara Y, Higuchi N, Tanaka Y, Oya M, Nakamura K:
Endoscopic submucosal dissection using a grasping-type scissors forceps for early gastric cancers and adenomas.
Dig Endosc 23: 24-29, 2011
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Mizutani T, Akiho H, Khan WI, Murao H, Ogino H, Kanayama K, Nakamura K, Takayanagi R:
Persistent gut motor dysfunction in a murine model of T-cell-induced enteropathy.
Neurogastroenterol Motil 22: 196-203, 2010
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Yoshinaga M, Kitamura Y, Chaen T, Yamashita S, Tsuruta S, Hisano T, Ikeda Y, Sakai H, Nakamura K, Takayanagi R, Muto Y:
The simultaneous expression of peroxisome proliferator-activated receptor delta and cyclooxygenase-2 may enhance angiogenesis and tumor venous invasion in tissues of colorectal cancers.
Dig Dis Sci 54: 1108-1114, 2009
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Higuchi N, Sumida Y, Nakamura K, Itaba S, Yoshinaga S, Mizutani T, Honda K, Taki K, Murao H, Ogino H, Kanayama K, Akiho H, Goto A, Segawa Y, Yao T, Takayanagi R:
Impact of double-balloon endoscopy on the diagnosis of jejunoileal involvement in primary intestinal follicular lymphomas: a case series.
Endoscopy 41: 175-178, 2009
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Kubo H, Nakamura K, Itaba S, Yoshinaga S, Kinukawa N, Sadamoto Y, Ito T, Yonemasu H, Takayanagi R:
Differential diagnosis of cystic tumors of the pancreas by endoscopic ultrasonography.
Endoscopy 41: 684-689, 2009
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Ihara E, Moffat L, Borman MA, Amon JE, Walsh MP, MacDonald JA:
Ca2+-independent contraction of longitudinal ileal smooth muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate peptide.
Am J Physiol Gastrointest Liver Physiol 297: G361-370, 2009
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Sumida Y, Nakamura K, Kanayama K, Akiho H, Teshima T, Takayanagi R:
Preparation of functionally preserved CD4+CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell-transfer therapy.
Cytotherapy 10: 698-710, 2008
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Motomura Y, Ghia J-E, Wang H, Akiho H, El-Sharkawy RT, Collins M, Wan Y, McLaughlin JT, Khan WI:
Enterochromaffin cell and 5-hydroxytryptamine responses to the same infectious agent differ in Th1 and Th2 dominant environments.
Gut 57:475-481, 2008
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Sun X, Somada S, Shibata K, Muta H, Yamada H, Yoshihara H, Honda K, Nakamura K, Takayanagi R, Tani K, Podack ER, Yoshikai Y:
A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice.
Gastroenterology 134: 447-58, 2008
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Yoshinaga S, Gotoda T, Kusano C, Oda I, Nakamura K, Takayanagi R:
Clinical impact of endoscopic submucosal dissection for superficial adenocarcinoma located at the esophagogastric junction.
Gastrointest Endosc 67: 202-9, 2008
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Matsumoto M, Yoshimura R, Akiho H, Higuchi N, Kobayashi K, Matsui N, Taki K, Murao H, Ogino H, Kanayama K, Sumida Y, Mizutani T, Honda K, Yoshinaga S, Itaba S, Muta H, Harada N, Nakamura K, Takayanagi R:
Gastric emptying in diabetic patients by the (13)C-octanoic acid breath test: role of insulin in gastric motility.
J Gastroenterol 42: 469-74, 2007
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Kumashiro Y, Yao T, Aishima S, Hirahashi M, Nishiyama K, Yamada T, Takayanagi R, Tsuneyoshi M:
Hepatoid adenocarcinoma of the stomach: histogenesis and progression in association with intestinal phenotype.
Hum Pathol 38: 857-63, 2007
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Murata A, Akahoshi K, Sumida Y, Yamamoto H, Nakamura K, Nawata H:
Prospective randomized trial of transnasal versus peroral endoscopy using an ultrathin videoendoscope in unsedated patients.
J Gastroenterol Hepatol 22: 482-5, 2007
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Takahashi M, Nakamura K, Honda K, Kitamura Y, Mizutani T, Araki Y, Kabemura T, Chijiiwa Y, Harada N, Nawata H:
An inverse correlation of human peripheral blood regulatory T cell frequency with the disease activity of ulcerative colitis.
Dig Dis Sci 51: 677-686, 2006
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Honda K, Itaba S, Mizutani T, Sumida Y, Kanayama K, Higuchi N, Yoshinaga S, Akiho H, Kawabe K, Arita Y, Ito T, Nakamura K, Takayanagi R:
An increase in the serum amylase level in patients after peroral double-balloon enteroscopy: an association with the development of pancreatitis.
Endoscopy 38: 1040-1043, 2006
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Nakamura N, Yamamoto H, Yao T, Oda Y, Nishiyama K, Imamura M, Yamada T, Nawata H, Tsuneyoshi M:
Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade.
Hum Pathol 36: 828-837, 2005
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Honda K, Nakamura K, Matsui N, Takahashi M, Kitamura Y, Mizutani T, Harada N, Nawata H, Hamano S, Yoshida H:
Th1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis.
Inflamm Bowel Dis 11: 1044-1052, 2005
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Motomura Y, Khan WI, El-Sharkawy RT, Verma-Gandhu M, Verdu EF, Gauldie J, Collins SM:
Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1.
Gut 55: 662-670, 2005
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Chinen T, Kobayashi T, Ogata H, Takaesu G, Takaki H, Hashimoto M, Yagita H, Nawata H, Yoshimura A:
Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNγ and IL-4 are involved.
Gastroenterology 130: 373-88, 2006
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Akiho H, Deng Y, Blennerhassett P, Kanbayashi H, Collins SM:
Mechanisms underlying the maintenance of muscle hypercontractility in a model of post-infective gut dysfunction.
Gastroenterology 129: 131-141, 2005
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Itaba S, Chijiiwa Y, Matsuzaka H, Motomura Y, Nawata H:
Presence of C-type natriuretic peptide (CNP) in guinea pig caecum: role and mechanisms of CNP in circular smooth muscle relaxation.
Neurogastroenterol Motil 16: 375-82, 2004
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Nakamura K, Kitani A, Fuss I, Pedersen A, Harada N, Nawata H, Strober W:
TGF-β1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice.
J Immunol 172: 834-42, 2004
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Araki Y, Okamura S, Hussain SP, Nagashima M, He P, Shiseki M, Miura K, Harris CC:
Regulation of cyclooxygenase-2 expression by the Wnt and Ras pathway.
Cancer Res 63: 728-734, 2003
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Akiho H, Blennerhassett P, Deng Y, Collins SM:
Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells.
Am J Physiol Gastrointest Liver Physiol 282: 226-232, 2002
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