文部科学省科学研究費特定領域研究「性分化機構の解明」 *

研究成果

濱口 哲 HAMAGUCHI, Satoshi
新潟大学 自然科学系
研究項目A01 「性分化の分子基盤の解析」
研究課題 種間雑種・突然変異による性転換を用いたメダカ性決定/性分化制御機構の解明

2008年発表論文

Otake H., Shinomiya A., Kawaguchi A., Hamaguchi S., Sakaizumi M. The medaka sex-determining gene DMY acquired a novel temporal expression pattern after duplication of DMRT1. Genesis 46, 719-723, 2008

Otake H., Hayashi Y., Hamaguchi S., Sakaizumi M. The Y chromosome that lost the male-determining function behaves as an X chromosome in the medaka fish, Oryzias latipes. Genetics 179, 2157-2162, 2008

Sato T., Suzuki A., Shibata N., Sakaizumi M., Hamaguchi S. The novel mutant scl of the medaka fish, Oryzias latipes, shows no secondary sex characters. Zoological Science 25, 299-306, 2008

2007年発表論文

Matsuda M., Shinomiya A., Kinoshita M., Suzuki A., Kobayashi T., Paul-Prasanth B., Lau E., Hamaguchi S., Sakaizumi M., Nagahama Y. DMY gene induces male development in genetically female (XX) medaka fish. PNAS 104, 3865-3870, 2007

2006年発表論文

A. Shinomiya, M. Kato, M. Yaezawa, M. Sakaizumi, S. Hamaguchi. Interspecific hybridization between Oryzias latipes and Oryzias curvinotus causes XY sex reversal. Journal of Expeimental Zoology, in press.

Wild-derived XY sex-reversal mutants in the medaka, Oryzias latipes. Genetics, in press.

Shinomiya A., Kato M., Yaezawa M., Sakaizumi M., Hamaguchi S. Interspecific hybridization between Oryzias latipes and Oryzias Curvinotus causes XY sex reversal. Journal of Experimental Zoology 305A, 890-896, 2006

Otake, H., Shinomiya A., Matsuda M., Hamaguchi S., Sakaizumi M. Wild-derived XY sex-reversal mutants in the medaka, Oryzias latipes. Genetics 173, 2083-2090, 2006

2005年発表論文

T. Sato, T. Endo, K. Yamahira, S. Hamaguchi, M. Sakaizumi, Induction of female-to-male sex reversal by high temperature treatment in medaka, Oryzias latipes.Zoological Science, 22:985-988, 2005

Iwamatsu T., Kobayashi H., Hamaguchi S., Sagegami R., Shuo T. Estradiol-17β content in developing eggs and induced sex reversal of the medaka (Oryzias latipes). J. Exp. Zool., 303A:161-167, 2005

2004年発表論文

Hamaguchi S., Toyazaki Y., Shinomiya A., Sakaizumi M. The XX-XY sex-determination system in Oryzias luzonensis and O. mekongensis revealed by the sex ratio of the progeny of sex-reversed fish. Zool Sci 21:1015-1018, 2004

Shinomiya A., Otake H., Togashi K., Hamaguchi S., Sakaizumi M. Field survey of sex-reversals in the medaka, Oryzias latipes: genotypic sexing of wild populations. Zool. Sci., 21:613-619, 2004