文部科学省科学研究費特定領域研究「性分化機構の解明」 *

研究成果

松田 賢一 MATSUDA, Ken-ichi
京都府立医科大学 医学研究科
研究項目A02 「脳の性分化と行動の解析」
研究課題 神経ネットワークの性差構築機構とその分子基盤の解明

2009年発表論文

Mori H., Matsuda K. I. , Pfaff D. W., Kawata M. Sagittalis Nucleus: A novel hypothalamic nucleus. Journal of Neuroendocrinology 2009, in press

Kitagawa T., Matsuda K. I. , Inui S., Takenaka H., Katoh N., Itami S., Kishimoto S., Kawata M. Keratinocyte growth inhibition through the modification of Wnt signaling by androgen in balding dermal papilla cells. Journal of Clinical Endocrinology and Metabolism 2009, in press

Sakamoto H., Matsuda K. I. , Zuloaga D. G., Nishiura N., Takanami K., Jordan C. L., Breedlove S. M., Kawata M. Stress affects a gastrin-releasing peptide system in the spinal cord that mediates sexual function: Implications for psychogenic erectile dysfunction. PLoS One 4, e4276, 2009

Hirahara Y., Matsuda K. I. , Gao W., Arvanitis D. N., Kawata M., Boggs J. M. The localization and non-genomic function of the membrane-associated estrogen receptor in oligodendrocytes. Glia 57, 153-165, 2009

2008年発表論文

Matsuda K. I. , Sakamoto H., Kawata M. Androgen action in the brain and spinal cord for the regulation of male sexual behaviors. Current Opinion in Pharmacology 8, 747-752, 2008

Mori H., Matsuda K. I. , Pfaff D. W., Kawata M. A recently identified hypothalamic nucleus expressing estrogen receptor α. Proceedings of National Academy of Science U. S. A. 105, 13632-13637, 2008

Kawata M., Nishi M., Matsuda K. I. , Sakamoto H., Kaku N., Masugi-Tokita M., Fujikawa K., Hirahara-Wada S., Takanami K., Mori H. Steroid receptor in the brain-lessons learned from molecular imaging. Journal of Neuroendocrinology 20, 673-676, 2008

Matsuda K. I. , Sakamoto H., Mori H., Hosokawa K., Kawamura A., Itose M., Nishi M., Prossnitz E. R., Kawata M. Expression and Intracellular Distribution of the G protein-Coupled Receptor 30 in Rat Hippocampal Formation. Neuroscience Letters 441, 94-99, 2008

Wakabayashi Y., Tsujimura A., Matsuda K. I. , Yoshimura N., Kawata M. Appearance of LFA-1 in the initial stage of synaptogenesis developing hippocampal neurons. Archives of Histrogy and Cytology 71, 23-36, 2008

Sakamoto H., Matsuda K. I. , Zuloaga D. G., Hongu H., Wada E., Wada K., Jordan C. L., Breedlove S. M., Kawata M. Sexually dimorphic gastrin releasing peptide system in the spinal cord controls male reproductive functions. Nature Neuroscience 11, 634-6, 2008

Kaku N., Matsuda K. I., Tsujimura A., Kawata M. Characterization of nuclear import of the domain-specfic androgen receptor in association with importin α/β and Ran-GTP systems. Endocrinology 149, 3960-3669, 2008

Matsuda K. I., Nishi M., Takaya H., Kaku N., Kawata M. Intranuclear mobility of estrogen receptor α and progesterone receptors in association with nuclear matrix dynamics. Journal of Cellular Biochemistry 103, 136-148, 2008

2007年発表論文

Sakamoto H., Matsuda K. I., Hosokawa K., Nishi M., Morris J. F., Prossnitz E. R., Kawata M. Expression of GPR30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology 148, 5842-5850, 2007

Nishi M., Usuku T., Itose M., Fujikawa K., Hosokawa K., Matsuda K. I., Kawata M. Direct visualization of glucocorticoid receptor positive cells in the hippocampal regions using green fluorescent protein transgenic mice. Neuroscience 146, 1555-1560, 2007

Nakauchi H., Matsuda K. I., Ochiai I., Kawauchi A., Mizutani Y., Miki T., Kawata M. A differential ligand-mediated response of green fluorescent protein-tagged androgen receptor in living prostate cancer and non-prostate cancer cell lines. Journal of Histochemstry and cytochemistry 55, 535-544, 2007

Han F., Ozawa H., Matsuda K. I., Lu H., De Kloet E. R., Kawata M. Changes in the expression of corticotrophin-releasing hormone, mineralocorticoid receptor and glucocorticoid receptor mRNAs in the hypothalamic paraventricular nucleus induced by fornix transection and adrenalectomy. Journal of Neuroendocrinology 19, 229-238, 2007

2006年発表論文

Pei M., Matsuda K., Sakamoto H., Kawata M. Intrauterine proximity to male fetuses affects the morphology of the sexually dimorphic nucleus of the preoptic area in the adult rat brain. Eur. J. Neurosci. 23,1234-1240, 2006

2005年発表論文

Han F., Ozawa H., Matsuda K., Nishi M., Kawata M. Colocalization of mineralocorticoid receptor and glucocorticoid receptor in the hippocampus and hypothalamus. Neurosci. Res. 51, 371-381,2005

Mori K., Matsuda K. I., Furusawa T., Kawata M., Inoue T., and Obinata M. Subcellular Localization and Dynamics of MysPDZ (Myo18A) in Live Mammalian Cells. Biochem. Biophys. Res. Commun. 326, 491-498, 2005