文部科学省科学研究費特定領域研究「性分化機構の解明」 *

研究成果

西森 克彦 NISHIMORI, Katsuhiko
東北大学 大学院農学研究科
研究項目A02 「脳の性分化と行動の解析」
研究課題 オキシトシン・受容体系による動物の社会行動樹立の性二型性制御メカニズムの解析

2009年発表論文

Yoshida, M., Takayanagi,Y., Inoue,K., Kimura,T., Young,L.J., Onaka,T., and Nishimori,K. "Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice. " J.Neuroscience 2009, in press

2008年発表論文

Nishimori, K., Takayanagi, Y., Yoshida, M. Kasahara, Y. Young, L. J. & Kawamata, M. "New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behaviour and control of energy balance." Prog. Brain Res. 170, 79-90, 2008

Mohri,Y., Kato,S., Umezawa,A., Okuyama,R., and Nishimori, K. "Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4." Dev.Dynamics 237, 2235-2242, 2008

Takayanagi, Y., Kasahara, Y., Onaka, T., Takahashi, N., Kawada, T., & Nishimori, K. "Oxytocin receptor-deficient mice developed late-onset obesity" Neuroreport 19, 951-955, 2008

Kawamata,M., Yoshida,M., Sugimoto,Y,, Kimura,T., Tonomura,Y., Takayanagi,Y., Yanagisawa,T., and Nishimori,K. "Infusion of oxytocin induces successful delivery in prostanoid FP-receptor-deficient mice" Mol.Cell Endocrinol. 283, 32-37, 2008

2007年発表論文

Kasahara,Y., Takayanagi,Y., Kawada,T., Itoi,K., and Nishimori,K. "Impaired Thermoregulatory Ability of Oxytocin-deficient Mice during Cold-exposure" Biosci.Biotechnol. Biochem. 2007, in press

Kawamata,M., Yoshida,M., Sugimoto,Y., Kimura,T., Tonomura,Y., Takayanagi,Y., Yanagisawa,T., and Nishimori,K. "Infusion of oxytocin induces successful delivery in prostanoid FP-receptor- deficient mice." , Mol.Cell.Endocrinol. 2007, in press

Kawamata,M., Inoue,H., and Nishimori,K. "Male-specific function of Dmrt7 by sexually dimorphic translation in mouse testis." Sex Differentiation, 2007, in press

Kato,S., Mohri,M., Matsuo,T., Ogawa,E., Umezawa,A., Okuyama,R., & Nishimori,K., "Eye-open at birth phenotype with reduced keratinocyte motility in LGR4 null mice." FEBS Letter 581, 4685-4690, 2007

Tanino, T., Nawa, A., Kondo, E., Kikkawa, F., Daikoku, T. Tsurumi, T., Luo, C., Nishiyama, Y., Takayanagi, Y., Nishimori,K., Ichida, S. Wada,T., Miki, Y. & Iwaki,M. "Paclitaxel-2'- Ethylcarbonate Prodrug Can Circumvent P- glycoprotein-mediated Cellular Efflux to Increase Drug Cytotoxicity." Pharm Res : 24, 555-565, 2007

Hidema,S., Maruyama,T., Kato,S., and Nishimori,K., "Highly Induced DNA Recombination Mediated by Membrane Permeabilized Recombinant Cre Protein in Mouse Primary Cells" Biosci.Biotechnol.Biochem. 71 (3), 817-820, 2007

Maruyama,T., Hatakeyama,S., Miwa,T., Nishimori,K., "Human Smooth Muscle a-Actin Promoter Drives Cre Recombinase Expression in Cranial Suture in Addit ion to Smooth Muscle Cells.", Biosci.Biotechnol.Biochem. 71; 1103-1106, 2007

Kawamata,M., Tonomura,Y., Kimura,T., Yanagisawa,T., and *Nishimori,K. "Oxytocin- induced phasic and tonic contractions are modulated by the contractile machinery rather than the quantity of oxytocin receptor." Am.J.Physiol.Endocrinol. Metab.292;E992-E999, 2007