文部科学省科学研究費特定領域研究「性分化機構の解明」 *

研究成果

佐藤 陽一 SATO, Youichi
徳島大学 大学院ヘルスバイオサイエンス研究部
研究項目A01 「性分化の分子基盤の解析」
研究課題 ヒト性分化機構に対するプロテオミクスからのアプローチ

2009年発表論文

Sato Y, Shinka T, Chen G, Yan HT, Sakamoto K, Ewis AA, Aburatani H, Nakahori Y. Proteomics and transcriptome approaches to investigate the mechanism of human sex determination. Cell Biol. Int. In press

2007年発表論文

Yan HT, Shinka T, Sato Y, Yan HT, Chen G, Sakamoto K, Kinoshita K, Aburatani H, Nakahori Y. Overexpression of SOX15 Inhibits Proliferation of NT2/D1 Cells Derived from a Testicular Embryonal Cell Carcinoma. Mol. Cells 24, 323-328, 2007

2006年発表論文

Ewis AA, Lee J, Naroda T, Kagawa S, Baba Y, Nakahori Y. Lack of association between the incidence of testicular germ cell tumors and Y-chromosome haplogroups in the Japanese population. Int. J. Urol. 13, 1212-1217, 2006

Jabasini M, Ewis AA, Fouad M, Dang F, Ping G, Shinka T, Nakahori Y, Kaji N, Tokeshi M, Baba Y. Rapid multiplexing and simultaneous detection of human spermatogenetic failure with a 12 lane microchip electrophoresis system. Biol. Pharm. Bull. 29, 1487-1489, 2006

Ewis AA, Kondo K, Dang F, Nakahori Y, Shinohara Y, Ishikawa M, Baba Y. Surfactant protein B gene variations and susceptibility to lung cancer in chromate workers. Am. J. Ind. Med. 49, 367-373, 2006

Ewis AA, Lee J, Naroda T, Sano T, Kagawa S, Iwamoto T, Shinka T, Shinohara Y, Ishikawa M, Baba Y, Nakahori Y. Prostate cancer incidence varies among males from different Y-chromosome lineages. Prostate Cancer Prostatic Dis. 9, 303-309, 2006

Sato Y, Yoshida K, Shinka T, Nozawa S, Nakahori Y, Iwamoto T. Altered expression pattern of heat shock transcription factor, Y chromosome (HSFY) may be related to altered differentiation of spermatogenic cells in testes with deteriorated spermatogenesis. Fertil. Steril. 86, 612-618, 2006

Mori T, Kurahashi H, Shinka T, Nakahori Y, Taniguchi M, Toda T, Iwamoto T. Candidate genes for male factor infertility--validation. Fertil. Steril. 86, 1553-1554, 2006

Mayumi Umeno, Toshikatsu Shinka, Youichi Sato, Xin-Jun Yang, Yoshinobu Baba, Teruaki Iwamoto and Yutaka Nakahori. A rapid and simple system of detecting deletions on the Y chromosome related with male infertility using multiplex PCR. J. Med. Invest. 53(1, 2), 147-152, 2006

Keigo Kinoshita, Toshikatsu Shinka, Youichi Sato, Hiroki Kurahashi, Hiroe Kowa, Gang Chen, Mayumi Umeno, Kazunori Toida, Emi Kiyokage, Takuro Nakano, Susumu Ito and Yutaka Nakahori. Expression analysis of a mouse orthologue of HSFY, a candidate for the azoospermic factor on the human Y chromosome. J. Med. Invest. 53(1, 2), 117-122, 2006

2005年発表論文

Xin-Jun Yang, Toshikatsu Shinka, Shiari Nozawa, Hong-Tao Yan, Miki Yoshiike, Mayumi Umeno, Youichi Sato, Gang Chen, Teruaki Iwamoto, and Yutaka Nakahori. Survey of the two polymorphisms in DAZL, an autosomal candidate for the azoospermic factor, in Japanese infertilemen and implications for male infertility. Mol. Hum. Reprod. 11(7), 513-515, 2005

Yan HT, Shinka T, Kinoshita K, Sato Y, Umeno M, Chen G, Tsuji K, Unemi Y, Yang XJ, Iwamoto T, Nakahori Y. Molecular analysis of TBL1Y, a Y-linked homologue of TBL1X related with X-linked late-onset sensorineural deafness. J Hum Genet. 50, 175-181, 2005

2004年発表論文

Shinka T., Sato Y, Gang Chen, Naroda T., Kinoshita K., Unemi Y., Tsuji K., Toida K., Iwamoto T., Nakahori Y. Molecular characterization of HSFY, HSF-like factor encoded on the human Y chromosome, and implications for male infertility. Biol Reprod, 71, 297-306, 2004