Study

 

 

■Research fields
#1 Human brain function (see figure)
1) A combined study of electro-magnetophysiology and neuroimaging analyses on human higher brain function and basal ganglia (Depts. of Neurology, Neurosurgery, Otorhinolaryngology, Clinical Radiology, Experimental Psychology and Electrical and Electronic Systems Engineering).
2) Interhemispheric functional correlation among the primary sensory areas using coherence analysis.
3) Physiological significance of the induced and evoked gamma oscillations of the higher visual areas using wavelet transformation.

#2 Development of new techniques for the diagnosis and treatment of neurological diseases
1) A clinico-electrophysiological study on Alzheimer disease (Depts. of Neurology and Psychiatry).
Treatment of the neurological and psychiatrical diseases with repetitive transcranial magnetic stimulation (Depts. of Neurology, Psychiatry and Urology).
2) Mechanisms of photosensitive epilepsy (Dept. of Pediatrics, Fukuoka University).
3) Clinical significance of the soleus late response in cerebellar ataxia and basal ganglia diseases (Dept. of Neurology).

#3 Experimental studies on animal models for neurological and ophthalmological diseases
1) An electrophysiological analysis of changes in response properties of GABAA receptor of the pyramidal cells under hippocampal sclerosis (Dept. of Cellular and System Physiology
2) An electrophysiological analysis of the retinal function of rats after the retinal gene transfer (Dept. of Pathophysiology and Experimental Pathology and Ophthalomology)
3) A study on the function of glutamergic receptors and glutamate transporter in rats with kainic acid induced hippocampal seizures (Dept. of Neuropathology)

■Published papers
1) Tobimatsu S et al. Recent advances in clinical neurophysiology of vision. Electroenceph clin Neurophysiol (suppl), 53: 312-322, 2000.
2) Tobimatsu S et al. Differential temporal coding of the vibratory sense in the hand and foot in man. Clin Neurophysiol, 111 (3): 398-404, 2000.
3) Arakawa K et al. Effect of stimulus orientation on the VEP spatial frequency function.Exp Brain Res, 131 (1): 121-125, 2000.
4) Ishibashi H et al. Differential interaction of somatosensory inputs in the human primary sensory cortex: A magnetoencephalographic study. Clin Neurophysiol, 111 (6): 1095-1102, 2000.
5) Shigematsu J et al. Recovery of brain dysfunction after methyl mercury exposure in rats. J Neurol Sci, 182 (1): 61-68, 2000.
6) Shigematsu J et al. Chronic effects of methylmercury on the cerebral function in rats. J Neurol Sci, 182 (1): 69-75, 2000.
7) Gondo K et al. A magnetoencephalographic study on development of the somatosensory cortex in infants. NeuroReport, 12 (15): 3227-3231, 2001.
8) Goto Y et al. Magnesium deficiency differentially affects the retina and visual cortex of intact rats.
J Nutr, 131 (9): 2378-2381, 2001.
9) Suga R et al. The soleus late response elicited by transcranial magnetic stimulation reflects agonist-antagonist postural adjustment in the lower limbs. Clin Neurophysiol, 112 (12): 2300-2311, 2001.
10) Goto Y et al. Different vulnerability of rat retinal cells to methylmercury exposure. Curr Eye Res, 23 (3): 171-178, 2001.