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(班員専用です)
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| 小林 慎 KOBAYASHI, Shin |
| 大阪大学 遺伝情報実験センター(平成17年度〜平成18年度) 東京医科歯科大学 難治疾患研究所(平成19年度〜平成20年度) |
| 研究項目A01 「性分化の分子基盤の解析」 |
| 研究課題 哺乳類の雄雌はいつ異なり始めるのか?(平成17年度〜平成18年度) |
| 雌雄で発現が異なるインプリント遺伝子群の解析(平成19年度〜平成20年度) |
2009年発表論文Okada Y, Ueshin Y, Hasuwa H, Takumi K, Okabe M, Ikawa M. Targeted gene modification in mouse ES cells using integrase-defective lentiviral vectors. Genesis. 2009 [Epub ahead of print] Yamaguchi R, Yamagata K, Hasuwa H, Inano E, Ikawa M, Okabe M. Cd52, known as a major maturation-associated sperm membrane antigen secreted from the epididymis, is not required for fertilization in the mouse. Genes Cells. 13, 851-61, 2009 2008年発表論文Inoue N, Ikawa M, Okabe M. Putative sperm fusion protein IZUMO and the role of N-glycosylation. Biochem Biophys Res Commun. 377, 910-914, 2008 2007年発表論文Okada Y, Ueshin Y, Isotani A, Saito-Fujita T, Nakashima H, Kimura K, Mizoguchi A, Oh-Hora M, Mori Y, Ogata M, Oshima RG, Okabe M, Ikawa M. Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer. Nat Biotechnol. 25, 233-7, 2007 Epub 2007 Jan 14. 2006年発表論文Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T. Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 113, 223-9, 2006 Kobayashi S, Isotani A, Mise N, Yamamoto M, Fujihara Y, Kaseda K, Nakanishi T, Ikawa M, Hamada H, Abe K, Okabe M. Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the x-linked gene, rhox5/pem, at preimplantation stages. Curr Biol. 2006 Jan 24;16(2):166-72. 2005年発表論文Isotani A, Nakanishi T, Kobayashi S, Lee J, Chuma S, Nakatsuji N, Ishino F, Okabe M. Genomic imprinting of XX spermatogonia and XX oocytes recovered from XX<-->XY chimeric testes. Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4039-44. Epub 2005 Mar 3. Suzuki S, Renfree MB, Pask AJ, Shaw G, Kobayashi S, Kohda T, Kaneko-Ishino T, Ishino F. Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby. Mech Dev. 2005 Feb;122(2):213-22. |