Research list

2022.11.02

Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis

Assistant Professor Masataka Ikeda (Donated Fund Laboratory Department of Immunoregulatory Cardiovascular Medicine [Department of Cardiovascular Medicine]) has published their reaserch results.
Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis
Ko Abe, Masataka Ikeda, Tomomi Ide, Tomonori Tadokoro, Hiroko Deguchi Miyamoto, Shun Furusawa, Yoshitomo Tsutsui, Ryo Miyake, Kosei Ishimaru, Masatsugu Watanabe, Shouji Matsushima, Tomoko Koumura, Ken-ichi Yamada, Hirotaka Imai, Hiroyuki Tsutsui
10.1126/scisignal.abn8017

For more information, please see below.
Cardio-Oncology
Press release(JPN)
【Contact】
Kyushu University Faculty of Medical Sciences Donated Fund Laboratory Department of Immunoregulatory Cardiovascular Medicine [Department of Cardiovascular Medicine])
Assistant Professor Masataka Ikeda 
TEL:+81 92-642-5360
Mail:ikeda-m★cardiol.med.kyushu-u.ac.jp
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